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. 2009 Oct 7;2009(4):CD003246. doi: 10.1002/14651858.CD003246.pub2

Griffith‐Jones 1990.

Methods RCT.
Participants 200 women. Singleton, cephalic, mixed parity, ruptured membranes.
No evidence of contractions more frequent than every 20 minutes or evidence of clinical infection.
Interventions IV oxytocin (maximum dose for primiparous women 50 mU/min, multiparous women 10 mU/min) 
 vs 
 3 mg vaginal PGE2 pessary repeated after 6 hours.
Outcomes C/S, instrumental vaginal delivery, uterine hyperstimulation, Apgar score.
Notes Randomisation schedule from random number tables, concealment by sealed, sequentially numbered opaque envelopes.
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk Random number tables.
Allocation concealment? Low risk Sequentially numbered, opaque, sealed envelopes.
Blinding? 
 Women High risk  
Blinding? 
 clinical staff High risk  
Blinding? 
 outcome assessor High risk  
Incomplete outcome data addressed? 
 All outcomes Low risk All women followed up.
Free of selective reporting? Low risk