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. 2009 Oct 7;2009(4):CD003246. doi: 10.1002/14651858.CD003246.pub2

Ulmsten 1979.

Methods RCT.
Participants 100 primips, term, intact membranes, singleton, cephalic.
Interventions IV oxytocin. 2 mU increasing every 30 minutes to a maximum dose of 24 mU 
 vs 
 intracervical PGE2 0.5 mg x 1.
ARM was not performed until labour was well established and cervical dilatation was greater than 4 cm.
Outcomes Vaginal delivery not achieved in 24 hrs, uterine hyperstimulation with FHR changes, C/S, uterine hyperstimulation without FHR changes, instrumental vaginal delivery, Apgar score < 7 at 5 minutes, maternal nausea, maternal vomiting, maternal diarrhoea.
Notes No mention of randomisation technique or allocation concealment.
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk No information.
Blinding? 
 Women High risk Different treatments compared.
Blinding? 
 clinical staff High risk  
Blinding? 
 outcome assessor High risk  
Free of selective reporting? Low risk