Ulmsten 1979.
Methods | RCT. | |
Participants | 100 primips, term, intact membranes, singleton, cephalic. | |
Interventions | IV oxytocin. 2 mU increasing every 30 minutes to a maximum dose of 24 mU
vs
intracervical PGE2 0.5 mg x 1. ARM was not performed until labour was well established and cervical dilatation was greater than 4 cm. |
|
Outcomes | Vaginal delivery not achieved in 24 hrs, uterine hyperstimulation with FHR changes, C/S, uterine hyperstimulation without FHR changes, instrumental vaginal delivery, Apgar score < 7 at 5 minutes, maternal nausea, maternal vomiting, maternal diarrhoea. | |
Notes | No mention of randomisation technique or allocation concealment. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | No information. |
Blinding? Women | High risk | Different treatments compared. |
Blinding? clinical staff | High risk | |
Blinding? outcome assessor | High risk | |
Free of selective reporting? | Low risk |