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Incidence of Uterine Adenocarcinomas in Wild-type and ERΔ3 Transgenic Mice with and without DES Exposure
| Age | UNTREATED
|
DES-TREATED
|
||
|---|---|---|---|---|
| WT | ERΔ3 | WT | ERΔ3 | |
| 8 months | 0% (0/21) | 0% (0/28) | 49% (17/35) | 81% (21/26)* |
| 12 months | 0% (0/17) | 10% (2/20) | 72% (13/18) | 86% (12/14) |
p<0.016, Fisher’s Exact Test
DES. Diethylstilbestrol; WT, wild-type (FVB/N strain)
