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. 2014 May 6;4(2):88–94. doi: 10.1159/000362566

Table 1.

Definition of the five subtypes of CRS

CRS Definition
CRS type 1 Acute worsening of heart function leading to AKI
CRS type 2 Chronic abnormalities in heart function leading to progressive CKD
CRS type 3 Acute worsening of kidney function leading to acute heart dysfunction
CRS type 4 CKD leading to chronic heart disease
CRS type 5 Cardiac and renal dysfunction due to acute or chronic systemic disorders