Table 1.
Clinical characteristics and comparisons of biomarker values between AD patients and controls
| AD | Controls | p values | |
|---|---|---|---|
| Age | 67.15 (59.90–74.31) | 60.56 (56.74–63.90) | |
| Gender, n (male/female) ApoE, % | 9/16 | 9/16 | |
| ε 2/3 | 4 | 4 | |
| ε 3/3 | 36 | 96 | |
| ε 3/4 | 48 | 0 | |
| ε 4/4 | 12 | 0 | |
| MMSE | 21.00 (18.00–24.00) | 29.00 (28.00–30.00) | |
| Chitotriosidase, nkat/l | 2.89 (1.39–3.84) | 1.24 (0.73–1.68) | 0.0007 |
| MCP-1, pg/ml | 613.00 (537.00–722.00) | 569.00 (474.00–645.00) | n.s. |
| YKL-40, ng/ml | 199,211.00 (165,877.00–25,572.00) | 112,631.00 (83,709.00–138,258.00) | <0.0001 |
| Aβ42, pg/ml | 326.00 (273.70–370.00) | 750.00 (663.92–851.10) | <0.0001 |
| T-tau, pg/ml | 873.50 (713.90–1,059.90) | 206.50 (155.89–240.66) | <0.0001 |
| P-tau, pg/ml | 121.70 (100.68–144.85) | 46.40 (40.50–59.00) | <0.0001 |
Values are medians with interquartile ranges in parentheses, except where otherwise indicated. ApoE = Apolipoprotein E; n.s. = not significant.