TABLE 2.
Radiation-induced genomic instability as measured by the GFP-based assay in three transfected clones of GM10115 cellsa
| Clone and X-ray dose (Gy) | Total no. of colonies scored | GFP+/− colonies (%) | SE (%) |
|---|---|---|---|
| TG9 | |||
| 0 | 449 | 2.07 | 0.92 |
| 1.0 | 587 | 2.18 | 0.64 |
| 2.5 | 559 | 5.46* | 0.88 |
| GH1 | |||
| 0 | 485 | 5.32 | 0.81 |
| 1.0 | 432 | 9.53* | 0.71 |
| 2.5 | 395 | 14.67* | 1.86 |
| GH24 | |||
| 0 | 646 | 2.45 | 1.10 |
| 1.0 | 727 | 6.30 | 1.10 |
| 2.5 | 690 | 9.09* | 1.40 |
a
Surviving fraction is the percentage of GM10115 cells surviving the given dose of radiation as determined by clonogenic survival. *, P < 0.05. Ten plates were used at each dose.