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. 2014 Aug 1;29(10):2339–2351. doi: 10.1093/humrep/deu200

Table I.

Reproductive outcome in girls with or without menstrual irregularity at 16 years of age.

Menstrual irregularitya at 16 years Nb Reproductive outcome at 26 years
P-value
No pregnancies (N/%) At least one pregnancy (N/%)
No 1252 402/32.1 850/67.9
Yes 482 154/32.0 328/68.0 0.950
No deliveries (N/%) At least one delivery (N/%)
No 1252 900/71.9 352/28.1
Yes 482 358/74.3 124/25.7 0.318
No miscarriagesc (N/%) At least one miscarriagec (N/%)
No 850 747/87.9 103/12.1
Yes 328 290/88.4 38/11.6 0.801
Number of pregnancies [mean (SD)]
No 1252 0.71 (1.18)
Yes 482 0.64 (1.10) 0.249
Number of deliveries [mean (SD)]
No 1252 0.47 (0.88)
Yes 482 0.44 (0.86) 0.410
Number of miscarriagesc [mean (SD)]
No 850 0.16 (0.48)
Yes 328 0.15 (0.46) 0.712

The significance tests used are the Chi-squared (χ2) test and Student's t-test.

aIn the 26-year questionnaire, women who reported menstruation cycle longer than 35 days (option 3), extremely irregular (option 4) or had amenorrhoea (option 5) were considered to have ‘menstrual irregularity’.

bThe numbers of non-symptomatic and symptomatic women in separate analyses varies due to non-response to some items.

cWomen who had not been pregnant by the age of 26 were excluded from the miscarriage analysis.