Table V.
Hormonal and anthropometric parameters of girls categorized by menstrual irregularity at the start of the study and with or without PCOS 10 years later.
| Menstrual irregularityA No PCOSB (n = 362–410) |
Menstrual irregularityA PCOSB,b (n = 43–50) |
P-value | |||
|---|---|---|---|---|---|
| Median (IQR) | Na | Median (IQR) | Na | ||
| Testosterone (nmol/l) | 1.63 (1.31, 2.06) | 367 | 1.95 (1.63, 2.37) | 43 | 0.001 |
| SHBG (nmol/l) | 48.7 (36.1, 64.9) | 368 | 46.7 (31.4, 64.7) | 43 | 0.699 |
| FAI | 3.33 (2.29, 4.95) | 367 | 4.04 (2.73, 5.89) | 43 | 0.046 |
| BMI at 16 years | 20.3 (18.8, 22.0) | 399 | 20.3 (19.0, 22.8) | 45 | 0.620 |
| WHR at 16 years | 0.76 (0.74, 0.79) | 397 | 0.77 (0.73, 0.80) | 44 | 0.916 |
| Change in BMI between age 16 and 26 | 2.30 (0.79, 4.02) | 384 | 2.27 (1.13, 6.00) | 45 | 0.348 |
| BMI at 26 years | 22.5 (20.5, 25.1) | 410 | 22.0 (20.1, 29.4) | 50 | 0.784 |
| WHR at 26 years | 0.84 (0.79, 0.90) | 362 | 0.85 (0.79, 0.89) | 47 | 0.867 |
The values are presented as medians and IQR (from 25th to 75th percentile). The significance test used is the Mann–Whitney U-test.
WHR, waist-to-hip ratio.
AMenstrual irregularity: at start of study (i.e. age 16 years).
BPCOS: data at 10 years after start of study (i.e. age 26 years).
aThe number of individuals in separate analyses varies due to non-response to some items.
bWomen with either self-reported PCOS diagnosis or both menstrual irregularity and hirsutism.