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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Br J Sports Med. 2012 Jun 28;46(14):979–988. doi: 10.1136/bjsports-2011-090895

Table 5.

Relative risk reduction and numbers-needed-to-treat analyses for overall anterior cruciate ligament injury

Reference Overall ACL injury in group Female athletes per group Overall ACL incidence rates* RRR (95% CI) NNT to benefit (NNTB), NNT to harm (NNTH) (95% CI)
Hewett et al
 Control 5 463 0.11 49.4 187 NNTB
 Intervention 2 366 0.06 (−63.7, 84.4) (58 NNTB to ∞ to 149 NNTH)
Soderman et al
 Control 1 78 0.12 −403.2 19 NNTH
 Intervention 4 62 0.68 (−712.8, −211.6) (70 NNTB to ∞ to 9 NNTH)
Heidt et al
 Control 8 258 NA § 23.2 139 NNTB
 Intervention 1 42 (−498.3, 90.1) (17 NNTB to ∞ to 22 NNTH)
Myklebust et al
 Control 29 942 0.14 12.6 257 NNTB
 Intervention (First only) 23 855 0.06 (−19.0, 35.9) (52 NNTB to ∞ to 86 NNTH)
Olsen et al
 Control 9 778 0.10 67.9 127 NNTB
 Intervention 3 808 0.03 (14.4, 88.0) (61 NNTB to ∞ to 1334 NNTH)
Petersen et al
 Control 5 142 0.21 78.8 36 NNTB
 Intervention 1 134 0.04 (−27.4, 96.5) (17 NNTB to ∞ to 170 NNTH)
Gilchrist et al
 Control 18 583 0.34 73.4 44 NNTB
 Intervention 7 852 0.20 (50.0, 85.8) (27 NNTB to 136)
Steffen et al
 Control 5 947 0.08 29.4 644 NNTB
 Intervention 4 1073 0.06 (−46.8, 66.0) (135 NNTB to ∞ to 231 NNTH)
Total
 Control 80 4191 0.14 43.8 120 NNTB
 Intervention 45 4192 0.06 (28.9, 55.5) (74 NNTB to 316)
*

Relative incidence rate (per 1000 A*h).

NNT to benefit (NNTB) represents a beneficial preventive effect of the intervention.

NNT to harm (NNTH) indicates harmful effect of the intervention. Infinity (∞) means no beneficial or harmful effects.

§

Exposure information was not available in the original report.

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