Table 5.
Relative risk reduction and numbers-needed-to-treat analyses for overall anterior cruciate ligament injury
Reference | Overall ACL injury in group | Female athletes per group | Overall ACL incidence rates* | RRR (95% CI) | NNT to benefit (NNTB)†, NNT to harm (NNTH)‡ (95% CI) |
---|---|---|---|---|---|
Hewett et al | |||||
Control | 5 | 463 | 0.11 | 49.4 | 187 NNTB |
Intervention | 2 | 366 | 0.06 | (−63.7, 84.4) | (58 NNTB to ∞ to 149 NNTH) |
Soderman et al | |||||
Control | 1 | 78 | 0.12 | −403.2 | 19 NNTH |
Intervention | 4 | 62 | 0.68 | (−712.8, −211.6) | (70 NNTB to ∞ to 9 NNTH) |
Heidt et al | |||||
Control | 8 | 258 | NA § | 23.2 | 139 NNTB |
Intervention | 1 | 42 | (−498.3, 90.1) | (17 NNTB to ∞ to 22 NNTH) | |
Myklebust et al | |||||
Control | 29 | 942 | 0.14 | 12.6 | 257 NNTB |
Intervention (First only) | 23 | 855 | 0.06 | (−19.0, 35.9) | (52 NNTB to ∞ to 86 NNTH) |
Olsen et al | |||||
Control | 9 | 778 | 0.10 | 67.9 | 127 NNTB |
Intervention | 3 | 808 | 0.03 | (14.4, 88.0) | (61 NNTB to ∞ to 1334 NNTH) |
Petersen et al | |||||
Control | 5 | 142 | 0.21 | 78.8 | 36 NNTB |
Intervention | 1 | 134 | 0.04 | (−27.4, 96.5) | (17 NNTB to ∞ to 170 NNTH) |
Gilchrist et al | |||||
Control | 18 | 583 | 0.34 | 73.4 | 44 NNTB |
Intervention | 7 | 852 | 0.20 | (50.0, 85.8) | (27 NNTB to 136) |
Steffen et al | |||||
Control | 5 | 947 | 0.08 | 29.4 | 644 NNTB |
Intervention | 4 | 1073 | 0.06 | (−46.8, 66.0) | (135 NNTB to ∞ to 231 NNTH) |
Total | |||||
Control | 80 | 4191 | 0.14 | 43.8 | 120 NNTB |
Intervention | 45 | 4192 | 0.06 | (28.9, 55.5) | (74 NNTB to 316) |
Relative incidence rate (per 1000 A*h).
NNT to benefit (NNTB) represents a beneficial preventive effect of the intervention.
NNT to harm (NNTH) indicates harmful effect of the intervention. Infinity (∞) means no beneficial or harmful effects.
Exposure information was not available in the original report.