Table 1.

Definition of Adenocarcinoma in situ, Minimally Invasive Adenocarcinoma, and Nonmucinous Lepidic Predominant Invasive Adenocarcinoma

Subtype	Size and Invasion	Lepidic Pattern Distribution	Lymphatic Invasion	Vascular Invasion	Pleural Invasion	Tumor Necrosis
Adenocarcinoma in situ	≤3 cm and no invasion	100%	Absent	Absent	Absent	Absent
Minimally invasive adenocarcinoma	≤3 cm and ≤5 mm invasion	Predominant	Absent	Absent	Absent	Absent
Lepidic predominant invasive adenocarcinoma	>3 cm and/or >5 mm invasion	Predominant	Absent or present	Absent or present	Absent or present	Absent or present