. Author manuscript; available in PMC: 2015 Sep 11.

Published in final edited form as: Cell. 2014 Sep 11;158(6):1402–1414. doi: 10.1016/j.cell.2014.08.032

Table 1.

Minimum inhibitory concentration (MIC) of lactocillin against vaginal and oral pathogens and commensals (in nM). See Experimental Procedures for details.

Strain	Phylum	Description	Lactocillin MIC (nM)
*Staphylococcus aureus*	Firmicutes	Pathogen	42^a
*Escherichia coli*	Proteobacteria	Commensal	NA^b
*Enterococcus faecalis*	Firmicutes	Pathogen	425
*Lactobacillus jensenii*	Firmicutes	Vaginal commensal	NA^b
*Lactobacillus gasseri*^c	Firmicutes	Vaginal commensal	NA^b
*Lactobacillus crispatus*	Firmicutes	Vaginal commensal	NA^b
*Corynebacterium aurimucosum*	Actinobacteria	Vaginal pathogen	42^a
*Finegoldia magna*	Firmicutes	Vaginal pathogen	NA^b
*Gardnerella vaginalis*	Actinobacteria	Vaginal pathogen	212
*Streptococcus sanguinis*	Firmicutes	Oral commensal	212
*Streptococcus sobrinus*	Firmicutes	Oral commensal/pathogen	85
*Streptococcus mutans*	Firmicutes	Oral commensal/pathogen	425

Lowest concentration tested was 42 nM.

Highest concentration tested was 425 nM.

Note that the strain of L. gasseri tested was SV-16A-US, which is a different strain from the lactocillin producer (JV-V03).

Notes:

Streptococcus sanguinis and Gardnerella vaginalis were partially inhibited at 80 nM lactocillin, but not completely until the next concentration tested (212 nM).
Streptococcus mutans was partially inhibited at 212 nM, but not completely until the next concentration tested (425nM).