Nucleotomy decreased compression modulus (A), increased compressive strain (B), decreased neutral zone modulus at the initial and recovery hydration states and increased neutral zone modulus at the cyclic hydration state (C), and increased neutral zone strain (D). These findings indicate that nucleotomy induces hypermobility regardless of the disc’s hydration state. Solid = Intact, Checkered = Nucleotomy. *p < 0.05, #p < 0.1