Figure 3.
Q-TOF mass spectrometry analysis of reactants and products of the oligonucleotides containing exocyclic guanine lesions incubated with AlkB for 2 h. Data represent the −4 charge envelopes; multiple ion mass peaks associated with each envelope reflect mostly the number of 13C atoms in each −4 charge packet. The monoisotopic peak (all 12C, 14N, etc.) value is labeled above each peak envelope. (a) α-OH-PdG; (b) α-OH-PdG + AlkB; (c) γ-OH-PdG; (d) γ-OH-PdG + AlkB; (e) M1dG; and (f) M1dG + AlkB.