Table 3.
Subtypes of Autoimmune Pancreatitis
| Subtype of AIP | Type 1 | Type 2 |
|---|---|---|
| Other nomenclatures | AIP without GEL | AIP with GEL |
| IgG4-related | IgG4-unrelated | |
| LPSP | IDCP | |
| Prevalence | Asia>USA, EU | EU>USA>Asia |
| Age | High aged | Younger |
| Gender | Male>>Female | Male=Female (NS) |
| Symptoms | ||
| Obstructive jaundice | Often | Often |
| Abdominal pain | Rare | Common |
| Pancreas swelling | Common | Common |
| Serology | High serum IgG, IgG4, autoAbs (+) | Normal IgG, normal IgG4, autoAbs (−) |
| OOI | Sclerosing cholangitis | Unrelated with OOI |
| Sclerosing sialadenitis | ||
| Reteroperitoneal fibrosis | ||
| Others | ||
| Ulcerative colitis | Rare | Often |
| Steroid | Responsive | Responsive |
| Relapse | High rate | Rare |
AIP, autoimmune pancreatitis; GEL, granulocytic epithelial lesion; LPSP, lymphoplasmacytic sclerosing pancreatitis; IDCP, idiopathic duct-centric chronic pancreatitis; NS, not significant; OOI, other organ involvement.