Fig. 1.

Sustained virologic response (SVR) rates in patients with genotype 1 hepatitis C virus (HCV) infection treated by all-oral, interferon-free regimens. Data were from different studies and are therefore not comparable among agents (different inclusion criteria, different treatment durations, assessment of SVR at different time points; week 12 or 24). In each study, the results from the treatment group with the highest SVR were reported. ‘CC’ indicates IL28B rs12979860 genotype CC, and ‘G’ indicates genotype.

NR, nonresponse; Int, intolerant to pegylated interferon and ribavirin; Nuc, nucleos(t)ide inhibitor; RBV, ribavirin. *Subtype analysis included combined data for 12- and 24-week regimens.