Table 1.
Model parameters from prior data and experimental protocols
| Model parameter | Value |
|---|---|
| Cell resting potential | −61 mV |
| VC soma holding potential | −80 mV |
| CC soma holding potential | −60 mV |
| Clamp settling interval | 2 s |
| Membrane capacitivity (Cm) | 0.72 μF cm−2 |
| Membrane resistivity (Rm) | 63 kΩ cm2 |
| SR spine adjustment factor | 2.0 |
| SLM spine adjustment factor | 1.0 |
| Synapse sample rate (nominal) | 1 per 10 μm |
| SLM-SR boundary location | Varies by cell |
| External Mg2+ (NMDAR responses) | 50 μM |
| External Mg2+ (combined responses) | 1 mM |