Table 3.

Top 20 biological processes (ranking by odds ratio) significantly enriched in comparison between early-onset preeclampsia and controls.

GOBPID	Biological Process	Genes in Differentially Expressed List, n	Genes in GOBPID List	Odds Ratio	Adjusted p-value
GO:0031424	keratinization	2	8	101.47	0.0080
GO:0030225	macrophage differentiation	2	12	60.86	0.0133
GO:0018149	peptide cross-linking	2	16	43.45	0.0179
GO:0042742	defense response to bacterium	4	39	39.11	0.0005
GO:0032945	negative regulation of mononuclear cell proliferation	2	27	24.31	0.0192
GO:0009913	epidermal cell differentiation	2	35	18.40	0.0241
GO:0050868	negative regulation of T cell activation	2	37	17.35	0.0241
GO:0030855	epithelial cell differentiation	4	83	16.23	0.0057
GO:0002695	negative regulation of leukocyte activation	2	44	14.87	0.0305
GO:0051707	response to other organism	8	227	13.15	0.0001
GO:0042129	regulation of T cell proliferation	2	52	12.13	0.0329
GO:0007398	ectoderm development	3	100	9.61	0.0233
GO:0043627	response to estrogen stimulus	2	69	9.03	0.0386
GO:0002526	acute inflammatory response	2	70	8.90	0.0386
GO:0070663	regulation of leukocyte proliferation	2	71	8.77	0.0391
GO:0007204	elevation of cytosolic calcium ion concentration	2	77	8.06	0.0405
GO:0050865	regulation of cell activation	3	147	6.44	0.0329
GO:0008624	induction of apoptosis by extracellular signals	2	97	6.35	0.0476
GO:0045664	regulation of neuron differentiation	2	97	6.35	0.0476
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	2	98	6.29	0.0477