Table 3. Comparison of different genetic models for -308G/A polymorphism and OSAHS risk in subgroups.
Subgroup analysis | No of studies | No of cases | No of controls | I2 | PQ | ORG (95% CI) |
All model-free | 7 | 1291 | 993 | 15.6 | 0.31 | 1.84(1.47–2.32) |
All in HWE | 6 | 1187 | 890 | 14.6 | 0.32 | 1.77(1.40–2.25) |
Caucasian | 3 | 425 | 586 | 0.0 | 0.52 | 1.83(1.42–2.35) |
Asian | 4 | 866 | 407 | 48.2 | 0.12 | 1.92(1.18–3.13) |
1.86(1.18–2.94)* | ||||||
All allele | 7 | 1291 | 993 | 18 | 0.29 | 1.78(1.45–2.18) |
Caucasian | 3 | 425 | 586 | 0.0 | 0.58 | 1.71(1.37–2.13) |
Asian | 4 | 866 | 407 | 48.8 | 0.12 | 1.90(1.24–2.93) |
Abbreviation: HWE, Hardy–Weinberg equilibrium. Note: *mean an adjustment for HWE.