Kellstein 2004.

Methods	RCT, DB, DD, placebo and active controlled parallel group study, single oral dose. Medication administered when pain intensity was moderate to severe. Study duration 24 hours
Participants	Post‐operative dental surgery, third molar extraction Male and females Mean age 22 years (range 17 to 41 years) N = 355
Interventions	Lumiracoxib 400 mg, n = 101 Rofecoxib 50 mg, n = 102 Celecoxib 200 mg, n = 101 Placebo, n = 51
Outcomes	≥50% PR over six hours Time to onset of analgesia Use of rescue medication Adverse events
Notes	Oxford Quality Score: R1, DB2, W0. Total = 3
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Low risk	"double dummy"