Methods | R, DB, 3 parallel groups, single oral dose Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 15, 30, 45, 60, 90, 120 mins, then hourly to 6 hours, then at 8 and 24 hours |
Participants | Third molar extraction N = 75 M = 25, F = 50 Mea age 23 yrs |
Interventions | Diclofenac K 100 mg, n = 31 Diclofenac Na softgel 100 mg, n = 29 Placebo, n = 15 |
Outcomes | PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers using rescue medication Time to use of rescue medication Numbers with any adverse event and serious adverse events Withdrawals |
Notes | Oxford Quality Score: R2, DB2, W1 Rescue medication permitted at any time. No details of drug used |
DB - double blind; F - female; M - male; N - total number in trial; n - number in treatment arm; PI - pain intensity; PR - pain relief; PGE - patient global evaluation; std - standard; R - randomised; W - withdrawals