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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Apr 15;(2):CD004768. doi: 10.1002/14651858.CD004768.pub2
Methods R, DB, 3 parallel groups, single oral dose
Medication administered when baseline pain was of moderate to severe intensity
Pain assessed at 0, 15, 30, 45, 60, 90, 120 mins, then hourly to 6 hours, then at 8 and 24 hours
Participants Third molar extraction
N = 75
M = 25, F = 50
Mea age 23 yrs
Interventions Diclofenac K 100 mg, n = 31
Diclofenac Na softgel 100 mg, n = 29
Placebo, n = 15
Outcomes PI: std 4 point scale
PR: std 5 point scale
PGE: std 5 point scale
Numbers using rescue medication
Time to use of rescue medication
Numbers with any adverse event and serious adverse events
Withdrawals
Notes Oxford Quality Score: R2, DB2, W1
Rescue medication permitted at any time. No details of drug used

DB - double blind; F - female; M - male; N - total number in trial; n - number in treatment arm; PI - pain intensity; PR - pain relief; PGE - patient global evaluation; std - standard; R - randomised; W - withdrawals