Comparison 2. Subgroup analyses.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 VO2 max (ml/kg/min)	24	4191	Mean Difference (IV, Random, 95% CI)	−2.19[−2.48,−1.90]
1.1 “Dose” of intervention =/> 30 units	11	432	Mean Difference (IV, Random, 95% CI)	−2.78[−3.88,−1.69]
1.2 “Dose” of intervention < 30 units	13	416	Mean Difference (IV, Random, 95% CI)	−1.64[−2.15,−1.12]
1.3 Jadad score = 3 and above	7	341	Mean Difference (IV, Random, 95% CI)	−2.01[−2.90,−1.12]
1.4 Jadad score = 2 and below	15	458	Mean Difference (IV, Random, 95% CI)	−2.28[−3.47,−1.10]
1.5 Duration of intervention >12 weeks	10	420	Mean Difference (IV, Random, 95% CI)	−2.62[−3.76,−1.48]
1.6 Duration of intervention =/<12 weeks	14	428	Mean Difference (IV, Random, 95% CI)	−1.79[−2.33,−1.24]
1.7 Mean age > 55 years	15	540	Mean Difference (IV, Random, 95% CI)	−1.77[−2.50,−1.03]
1.8 Mean age =/< 55 years	9	308	Mean Difference (IV, Random, 95% CI)	−2.95[−4.25,−1.64]
1.9 Duration of follow up > 16 weeks	9	397	Mean Difference (IV, Random, 95% CI)	−2.74[−3.83,−1.65]
1.10 Duration of follow up =/< 16 weeks	15	451	Mean Difference (IV, Random, 95% CI)	−1.55[−2.17,−0.94]