. Author manuscript; available in PMC: 2014 Sep 15.

Published in final edited form as: Cochrane Database Syst Rev. 2005 Apr 18;(2):CD002229. doi: 10.1002/14651858.CD002229.pub2

Comparison 2. HRT vs placebo (secondary prevention only).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Death (all causes)	7	7453	Risk Ratio (M-H, Fixed, 95% CI)	1.08 [0.94, 1.25]
2 Death (CV cause)	7	7453	Risk Ratio (M-H, Fixed, 95% CI)	1.00 [0.82, 1.23]
3 Non-fatal MI	6	7393	Risk Ratio (M-H, Fixed, 95% CI)	1.01 [0.85, 1.20]
4 Stroke	7	7453	Risk Ratio (M-H, Fixed, 95% CI)	1.15 [0.97, 1.36]
5 Combined CV events and outcomes	6	6433	Risk Ratio (M-H, Fixed, 95% CI)	0.96 [0.89, 1.04]
6 Venous thromboembolism	7	7533	Risk Ratio (M-H, Fixed, 95% CI)	2.03 [1.36, 3.04]
7 Pulmonary embolus	5	6905	Risk Ratio (M-H, Fixed, 95% CI)	2.07 [1.04, 4.10]