Figure 5. Chromatin dynamics dependent on lamins. Four major groups of events that contribute to chromatin dynamics are represented in the large ellipses. Blue arrows indicate A type lamin pathways, purple arrows B type pathways. Lamin partners involved in chromatin regulation are indicated in the respective arrows. Some targets of lamin activity (HP1alpha, HDAC3, SREBP1, OCT-1) are common to lamin A and lamin B-related pathways or are misregulated in diverse diseases (SREBP1, OCT-1, HP1alpha). Targets affected in laminopathies are in yellow boxes. See text for references.