Figure 2.IgH and Myc genes are closer to nucleoli when on a NOR-bearing chromosome. (A) Idiograms depicting the position of the IgH and Myc gene loci as well as the presence or absence of NORs in the different mouse strains used in this study. (B) DNA immuno-FISH images of C57, CBA, and 129P3 B-cells. (C) Quantitation of the distance between gene loci and the closest nucleolus in C57, CBA, and 129P3 B-cells: IgH, cyan squares; Myc, yellow circles; nucleoli, orange; DAPI, gray. Scale bar = 1 µm. Also shown in (C) is the distance between simulated random genes and nucleoli, black triangles.