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. 2014 Aug 26;5(5):474–481. doi: 10.4161/nucl.36233

graphic file with name nucl-5-474-g4.jpg

Figure 4. Nucleolar tethering via NORs is a mechanism that contributes to nuclear organization and promotes gene pairing. (A) Idiograms depicting Chr12 and Chr 15, the position of the IgH and Myc gene loci as well as the presence or absence of NORs in the different mouse strains used in this study. (B) Schematic diagram summarizing the effects on chromosome territory position when a NOR on Chr 12 or Chr 15 is absent. (C) Schematic diagram summarizing the effects on IgH and Myc gene position when a NOR on Chr 12 or Chr 15 is absent.