Table 4. Spearman coefficients (p-value) for correlations between concentrations of isoprostanes, triglycerides, albumin, and neurocognitive proficiency scores (N = 32).
Parameter | Isoprostane-VI | Total Isoprostane-VI | 8,12-iso-iPF2α-VI Isoprostane | Serum Triglycerides | Serum Albumin | BOT2-Scores |
Isoprostane-VI | ||||||
Total Isoprostane-VI | 0.56 (0.00) | |||||
8,12-iso-iPF2α-VI Isoprostane | 0.57 (0.00) | 0.73 (0.00) | ||||
Serum Triglycerides | 0.26 (0.14) | 0.18 (0.31) | 0.45 (0.00) | |||
Serum Albumin | −0.21 (0.24) | −0.19 (0.28) | −0.40 (0.02) | −0.40 (0.03) | ||
BOT2-Scores | −0.27 (0.13) | −0.13 (0.48) | −0.41 (0.02) | −0.51 (0.00) | 0.56 (0.00) | |
KABC-II Scores | −0.54 (0.00) | −0.58 (0.00) | −0.61 (0.00) | −0.39 (0.03) | 0.35 (0.04) | 0.64 (0.00) |
Of all the forms of isoprostanes, only 8,12-iso-iPF2α-VI isoprostane had serum concentrations that consistently and negatively correlated with concentrations of serum albumin and neurology proficiency scores. Concentrations of serum albumin positively correlated with neurology proficiency scores in contrast to the trend for concentrations of triglycerides that negatively correlated with proficiency scores.