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. 2014 Sep 15;9(9):e107247. doi: 10.1371/journal.pone.0107247

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© 2014 Fujiwara et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Immunohistochemical staining for CD166 was performed using resected pancreatic tissues. (a) In the normal pancreas, CD166 was expressed strongly in the membrane of islet cells (black arrows) and weakly in normal pancreatic ductal cells (black arrowhead). (b) In some pancreatic cancer tissues, cancer cells were positive for CD166. Original magnification: 200×. Insets: 600×. (B) Kaplan-Meier survival analysis revealed that the intensity of CD166 expression in pancreatic cancer was not correlated with prognosis (p = 0.1473). (C) Flow cytometric analysis of CD166 expression in cells separated based on EpCAM expression. The positive expression rate (%) is indicated for each marker.