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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Exp Cell Res. 2014 Aug 13;327(2):171–182. doi: 10.1016/j.yexcr.2014.07.035

Figure 8. HTM cells plated on laminin 5 only form CLANs in the presence of mAb AP-5.

Figure 8

N27TM-2 HTM cells were plated on laminin 5 for 3 hrs in the absence (A) or presence (B) of the αvβ3 integrin-activating antibody AP-5 prior to fixation and labeling with phalloidin. CLANs did not form on laminin 5 alone but did so in the presence of soluble mAb AP-5. Spreading also appeared to be enhanced when cells were spread on laminin 5 in the presence of AP-5. Bar = 20 µm.