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. 2014 Sep 15;9(9):e107231. doi: 10.1371/journal.pone.0107231

Figure 3. Changes in histone acetyl-transferase 1 and Class IIa histone deacetylases in the liver.

Figure 3

Mice liver samples were freeze-clamped after 4 weeks of OA administration (During OA treatment) (A) or 4 weeks after the cessation of OA administration (Post-OA treatment) (B). Liver lysates from mice were immunoblotted with HAT1, phosphorylated (p-) and total (t-) HDAC 4 and 5 (Class IIa HDACs) and quantified for statistical analysis. Data are mean ± SE. *p<0.05, **p<0.01 vs. T2D mice. n = 5–8 mice per group.