Skip to main content
. 2014 Jun 21;15(5):721–738. doi: 10.1007/s10162-014-0472-x

FIG. 3.

FIG. 3

QTL genetic mapping cross. The cartoon depicts the QTL genetic mapping cross using one representative autosome. The 129S6 (filled chromosomes) and CBACa (open chromosomes) parental strains were mated to produce CBACa129S6F1 hybrids. The F1 mice were then backcrossed to 129S6 to generate 232 N2-129S6 mice. Each N2 mouse inherits two chromosomes: (1) an 129S6 chromosome from the 129S6 homozygous parent and (2) a potentially recombinant chromosome from the CBACa129S6F1 hybrid parent. Each N2 mouse carries a unique genetic background that depends on the crossover points in the CBACa129S6F1 hybrid parent.