Table 3.
Transcripts significantly up-regulated in metastasizing tumors in both cohorts
| Non-metastatic vs metastatic tumors | Lymph node metastasis vs non-metastatic tumors | Non-metastatic vs metastatic tumors (Riester et al.) |
||||
|---|---|---|---|---|---|---|
| Transcript | p-value | FC | p-value | FC | p-value | FC |
| COL6A2 | 0.0397 | 1.0967 | 0.7515 | 0.1176 | 0.0461 | 1.7263 |
| LMCD1 | 0.0248 | 1.1631 | 0.0036 | 1.7576 | 0.0196 | 1.7212 |
| FZD1 | 0.0287 | 1.5193 | 0.0878 | 1.1318 | 0.0055 | 1.0648 |
| MITF | 0.0364 | 1.6083 | 0.4593 | -0.3003 | 0.0164 | 1.0783 |
| EDNRA | 0.0051 | 1.6613 | 0.0181 | 1.0262 | 0.0177 | 1.4840 |
| EBF1 | 0.0211 | 1.7592 | 0.0168 | 1.8477 | 0.0149 | 1.0386 |
| TPST1 | 0.0199 | 1.7953 | 0.1975 | 0.8709 | 0.0318 | 1.1064 |
| AEBP1 | 0.0242 | 2.2697 | 0.0077 | 1.6563 | 0.0072 | 3.0447 |
| PALLD | 0.0344 | 2.3131 | 0.1163 | 0.9763 | 0.0104 | 1.4558 |
| GEM | 0.0121 | 2.3136 | 0.0000 | 3.2533 | 0.0219 | 1.5247 |
| PXDN | 0.0044 | 3.1464 | 0.0042 | 1.8611 | 0.0356 | 1.9232 |
| KITLG | 0.0110 | 3.3621 | 0.0537 | 1.6857 | 0.0323 | 1.1616 |
FC = Log 2 fold change differences.
Bold indicates significant p-values when comparing lymph node metastasis and non-metastatic tumors.