Table 2.
Crypt prevalence
| Patients without crypts | Patients with crypts | Patients with partial crypts | |
|---|---|---|---|
| Overall prevalence n- (%) | 927 (90.9%) | 64(6.3%) | 29 (2.8%) |
| Age- years (SD) | 52.5 (17.0) | 53.23 (16.2) | 54.9 (16.7) |
| Gender male/female (% male) | 565/362 (61%) | 42/22 (66%) | 15/14 (52%) |
| Final Diagnosis- n (%) | |||
| ICM | 214 (90.7%) | 12 (5.1%) | 10 (4.2%) |
| NICM | 342 (91.0%) | 24 (6.4%) | 10 (2.7%) |
| DCM | 120 (95.3%) | 5 (3.9%) | 1 (0.8%) |
| HtCM | 8 (73%) | 3 (27%)* | 0 |
| Inflammatory CM | 79 (89.8%) | 5 (5.7%) | 4 (4.5%) |
| HCM | 67 (87%) | 9 (11.7)* | 1 (1.3%) |
| ARVC | 2 (50%) | 0 | 2 (50%) |
| Congenital | 4 (67%) | 0 | 2 (33%) |
| Pericardial disease | 7 | 0 | |
| Other/ | 55 | 2 | |
| Phenotype negative inherited cardiomyopathy family members (including HCM) | 31 (72.1%) | 10 (23.3%)** | 2 (4.7%) |
| Phenotype negative HCM family members | 6 (67%) | 3 (33%)* | 0 |
| ‘Control’ group | 295 (96%) | 11 (3.6%)* | |
| Unknown | 45 (79%) | 5 (8.8%) | 7 (12.2%) |
Distribution of Crypts by gender, age and clinical diagnosis. Crypts >50% invagination into surrounding normal myocardium. Partial crypts 25-50% invagination. ICM – ischemic cardiomyopathy, NICM – non-ischemic cardiomyopathy, DCM – dilated cardiomyopathy, HtCM – hypertensive cardiomyopathy, HCM – hypertrophic cardiomyopathy, ARVC – arrhythmogenic right ventricular cardiomyopathy. T-tests performed between crypts > 50% group and no crypt group. *p < 0.05, **p < 0.01.