Table 1.
Demographic data of jaundiced (n = 47) and non-jaundiced GBC patients (n = 145)
| Jaundiced, n | Non-jaundiced, n | p-value | |
|---|---|---|---|
| Male gender | 21 | 45 | 0.088 |
| Mean age (range) | 57.5 ± 11.0(35-80) | 58.2 ± 10.2(23-83) | 0.725 |
| Postoperative hospital stay | 19.7 ± 13.3 (4–85) | 11.5 ± 6.4 (5–51) | < 0.001 |
| Associated gallbladder disease | 0.983 | ||
| Gallstones | 26 (55.3%) | 80 (55.2%) | |
| Gallbladder polyp | 1 (2.1%) | 3 (2.0%) | |
| Nil | 20 (42.6%) | 62 (42.8%) | |
| Tumor location | < 0.001 | ||
| Gallbladder neck | 28 (59.6) | 26 (17.9) | |
| Gallbladder body | 10 (21.3) | 70 (48.3) | |
| Gallbladder fundus | 9 (19.1) | 49 (33.8) | |
| Histologic type | 0.259 | ||
| Well differentiated | 2 (4.3) | 9 (6.2) | |
| Moderately differentiated | 41 (87.2) | 109 (75.2) | |
| Poorly differentiated | 4 (8.5) | 27 (18.6) | |
| Extent of liver resection | 0.590 | ||
| Major hepatectomy (>3 segments) | 4 | 4 | |
| Anatomical segments IV-V | 8 | 42 | |
| Gallbladder bed | 35 | 99 | |
| Extrahepatic bile duct resection | 44 (93.6) | 12 (8.3%) | < 0.001 |
| Pathologic extrahepatic bile duct invasion | 38 (80.9) | 12 (8.3%) | < 0.001 |
| Combined resection of adjacent organs | 11 (23.4%) | 4 (2.8%) | < 0.001 |
| Hepatic invasion | 26 (55.3%) | 64 (44.1%) | 0.183 |
| Lymph node metastasis | 30 (63.8%) | 72 (49.7%) | 0.091 |
| Vascular invasion | 2 (4.3) | 3 (2.1%) | 0.415 |
| pT | 0.019 | ||
| pT1-2 | 16 (34.1%) | 78 (53.8%) | |
| pT3-4 | 31 (65.9%) | 67 (46.2%) | |
| Intra-operative bleeding (mL) | 754.3 ± 600.9 (200–3200) | 386.0 ± 251.8(200–1800) | 0.001 |
| Operative time (min) | 310.0 ± 82.7 (100–470) | 224.3 ± 77.3(100–400) | < 0.001 |
| R0 | 36 (76.6%) | 127 (87.6%) | 0.068 |
| Mortality (number of patients) | 3 (6.4%) | 3 (2.1%) | 0.141 |
| Morbidity (need invasive treatment) | 16 (34.0%) | 18 (12.4%) | 0.001 |
Note that adjacent organs include the pancreas, duodenum, stomach, and/or colon other than the liver and extrahepatic bile duct.