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. 2014 Sep 2;9:135. doi: 10.1186/s13023-014-0135-3

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© Chuang et al.; Licensee Biomedcentral Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Mass spectrum of DS and HS in urine, as well as the internal standards of different MPS phenotypes and normal controls. (A) Normal control; (B) MPS I- Scheie; (C) mild form of MPS II; (D) severe form of MPS II; (E) MPS IIIB; and (F) MPS VI. *Same pairs of transition mass-to-charge ratio for [²H₆] CS and [²H₆] DS dimers (m/z 432 → 239), and the retention time (minutes) for [²H₆] CS and [²H₆] DS dimers is 3.71 ± 0.09 and 3.26 ± 0.05 minutes, respectively.