Comparison 2.

Sensitivity analysis: pre-pregnancy intervention versus routine care: including all women randomised and not lost to follow up (Lumley study, pregnancy outcomes)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Became pregnant and had baby small-for-gestational age (< 10th percentile)	1	1013	Risk Ratio (M-H, Fixed, 95% CI)	1.33 [0.85, 2.10]
2 Became pregnant and had extremely preterm birth (less than 28 weeks)	1	1034	Risk Ratio (M-H, Fixed, 95% CI)	9.25 [0.50, 171.31]
3 Became pregnant and had preterm birth (less than 37 weeks)	1	1034	Risk Ratio (M-H, Fixed, 95% CI)	1.45 [0.79, 2.67]
4 Became pregnant and birthweight less than 2500 g	1	1034	Risk Ratio (M-H, Fixed, 95% CI)	1.84 [0.97, 3.50]
5 Became pregnant and baby had congenital anomaly	1	1039	Risk Ratio (M-H, Fixed, 95% CI)	2.57 [0.50, 13.20]