Table 2.
Survey of 25 case descriptions
| Case no. | Disease description | Grade |
|---|---|---|
| 1 | TOF, mild pulmonic stenosis | |
| 2 | Echo bright spot on left ventricular papillary muscles, otherwise normal heart structure and function | |
| 3 | HLHS, mitral atresia, aortic atresia, open unrestrictive atrial septum, no tricuspid regurgitation | |
| 4 | Midmuscular VSD, small | |
| 5 | Complete AV canal defect, mild AV valve regurgitation | |
| 6 | Left ventricle-to-right ventricle size discrepancy, left superior vena cava to coronary sinus, mild aortic arch narrowing | |
| 7 | Heterotaxy syndrome, single ventricle, pulmonary atresia, total anomalous pulmonary venous return (infradiaphragmatic) | |
| 8 | TGA (intact ventricular septum) | |
| 9 | Two-vessel umbilical cord, otherwise normal heart structure and function | |
| 10 | Double-outlet right ventricle, subaortic VSD with severe pulmonic stenosis | |
| 11 | HLHS, mitral stenosis, aortic atresia, intact atrial septum | |
| 12 | Floppy, redundant atrial septum and premature atrial contractions, otherwise normal heart structure and function | |
| 13 | TOF with pulmonary atresia, very small hypoplastic branch pulmonary arteries, and suspicion of multiple aortopulmonary collaterals | |
| 14 | Truncus arteriosus (type 2A with VSD and branch pulmonary arteries arising from side of trunk), no truncal valve stenosis or regurgitation | |
| 15 | Large perimembranous VSD | |
| 16 | Tricuspid atresia, normally related great vessels, moderate size VSD, moderate pulmonic stenosis | |
| 17 | Pulmonary atresia with intact ventricular septum, marked right ventricular hypoplasia, severe tricuspid valve hypoplasia; inflow into the ventricle noted, but no tricuspid regurgitation seen | |
| 18 | Truncus arteriosus (type 1A with VSD and main pulmonary artery segment giving rise to well-formed branch pulmonary arteries) abnormal truncal valve with severe truncal insufficiency | |
| 19 | TGA, VSD, pulmonic stenosis | |
| 20 | Ebstein’s anomaly, pulmonary atresia, severe tricuspid regurgitation, severe hydrops | |
| 21 | Complete AV canal defect, balanced, no AV valve regurgitation | |
| 22 | Interrupted aortic arch type B, VSD, mild subaortic narrowing | |
| 23 | Critical aortic valve stenosis, normal size and functioning left ventricle | |
| 24 | Pulmonary atresia with intact ventricular septum, near normal size tricuspid valve, plate-like pulmonary atresia, moderate tricuspid regurgitation | |
| 25 | Coarctation of the aorta, normal left ventricle |
Fetal cardiologists were asked to assess each case and assign a severity grade from 1 to 7 to the case using the Fetal Cardiovascular Disease Severity Scale
TOF tetralogy of Fallot, HLHS hypoplastic left heart syndrome, AV atrioventricular, VSD ventricular septal defect, TGA transposition of the great arteries