Table 2.

Association of polymorphic variants of CDH1 with the risk of NSCL/P

rs no.	Allelesa	MAFb	Genotypes casesc	Genotypes controlsc	ptrend value	pgenotypic value	pallelic value	ORdominant (95 % CI)d; p value	ORrecessive (95 % CI)e; p value
rs16260	A/C	0.29	22/97/131	49/213/278	0.811	0.970	0.807	0.964 (0.714–1.301); 0.810	0.967 (0.571–1.638); 0.900
rs9929218	A/G	0.29	22/102/126	48/222/270	0.921	0.995	0.921	0.984 (0.729–1.328); 0.917	0.989 (0.583–1.678); 0.967
rs7186053	A/G	0.45	48/118/84	111/261/168	0.480	0.766	0.474	0.893 (0.648–1.229); 0.485	0.918 (0.630–1.340); 0.659
rs4783573	A/G	0.27	18/95/137	40/210/290	0.787	0.959	0.785	0.957 (0.708–1.293); 0.774	0.970 (0.544–1.728); 0.917
rs16958383	A/G	0.19	8/78/164	23/155/362	0.930	0.637	0.929	1.066 (0.777–1.464); 0.690	0.743 (0.328–1.686); 0.476
rs1801552	C/ T	0.36	18/125/107	75/240/225	0.126	0.021	0.129	0.955 (0.705–1.293); 0.764	0.481 (0.281–0.824); 0.007

Statistically significant results are highlighted in bold (p < 0.00833—Bonferroni correction)

^aUnderline denotes the minor allele in the control samples

^b MAF minor allele frequency calculated from the control samples

^cThe order of genotypes: dd/Dd/DD (d is the minor allele in the control samples)

^dDominant model: dd + Dd versus DD (d is the minor allele)

^eRecessive model: dd versus Dd + DD (d is the minor allele)