Comparison 11. Dropouts due to adverse events.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Milnacipran vs TCAs	6	756	Odds Ratio (M‐H, Random, 95% CI)	0.55 [0.35, 0.85]
1.1 Milnacipran vs Imipramine	4	562	Odds Ratio (M‐H, Random, 95% CI)	0.60 [0.35, 1.04]
1.2 Milnacipran vs Clomipramine	1	107	Odds Ratio (M‐H, Random, 95% CI)	0.43 [0.18, 1.03]
1.3 Milnacipran vs Amitriptyline	1	87	Odds Ratio (M‐H, Random, 95% CI)	0.56 [0.12, 2.49]
2 Milnacipran vs SSRIs	7	1143	Odds Ratio (M‐H, Random, 95% CI)	0.71 [0.48, 1.04]
2.1 Milnacipran vs Fluvoxamine	2	240	Odds Ratio (M‐H, Random, 95% CI)	0.51 [0.17, 1.47]
2.2 Milnacipran vs Fluoxetine	3	560	Odds Ratio (M‐H, Random, 95% CI)	0.70 [0.41, 1.19]
2.3 Milancipran vs Paroxetine	2	343	Odds Ratio (M‐H, Random, 95% CI)	0.82 [0.42, 1.62]
3 Milnacipran vs Heterocyclics	1	179	Odds Ratio (M‐H, Random, 95% CI)	0.78 [0.33, 1.87]
3.1 Milnacipran vs Mianserin	1	179	Odds Ratio (M‐H, Random, 95% CI)	0.78 [0.33, 1.87]