Comparison 23. Adverse events: Diarrhoea.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Milnacipran vs TCAs	5	656	Odds Ratio (M‐H, Random, 95% CI)	1.24 [0.29, 5.29]
1.1 Milancipran vs Imipramine	3	462	Odds Ratio (M‐H, Random, 95% CI)	0.47 [0.12, 1.75]
1.2 Milnacipran vs Clomipramine	1	107	Odds Ratio (M‐H, Random, 95% CI)	5.50 [0.26, 117.22]
1.3 Milnacipran vs Amitriptyline	1	87	Odds Ratio (M‐H, Random, 95% CI)	7.34 [0.37, 146.43]
2 Milancipran vs SSRIs	6	1102	Odds Ratio (M‐H, Random, 95% CI)	0.69 [0.37, 1.27]
2.1 Milnacipran vs Fluvoxamine	2	240	Odds Ratio (M‐H, Random, 95% CI)	0.76 [0.29, 2.00]
2.2 Milnacipran vs Fluoxetine	3	560	Odds Ratio (M‐H, Random, 95% CI)	0.70 [0.31, 1.58]
2.3 Milnacipran vs Paroxetine	1	302	Odds Ratio (M‐H, Random, 95% CI)	0.20 [0.01, 4.26]