Comparison 29. Subgroup analysis: Response at early phase [1‐4 weeks]‐Inpatient.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Milnacipran vs TCAs	3	342	Risk Ratio (M‐H, Random, 95% CI)	0.78 [0.60, 1.01]
1.1 Milancipran vs Imipramine	1	109	Risk Ratio (M‐H, Random, 95% CI)	0.85 [0.58, 1.24]
1.2 Milnacipran vs Amitriptyline	2	233	Risk Ratio (M‐H, Random, 95% CI)	0.73 [0.51, 1.04]
2 Milancipran vs SSRIs	3	468	Risk Ratio (M‐H, Random, 95% CI)	1.20 [0.86, 1.69]
2.1 Milnacipran vs Fluvoxamine	1	127	Risk Ratio (M‐H, Random, 95% CI)	1.53 [0.83, 2.79]
2.2 Milnacipran vs Fluoxetine	1	300	Risk Ratio (M‐H, Random, 95% CI)	1.34 [0.96, 1.87]
2.3 Milnacipran vs Paroxetine	1	41	Risk Ratio (M‐H, Random, 95% CI)	0.81 [0.47, 1.40]