Table 2.
Crude numbers of events and adjusted hazard ratios associated with different BMI groups for the individual endpoints
| 30-day MACE | 30-day mortality | 30-day CV mortality | 1-year mortality | 1-year CV mortality | |
|---|---|---|---|---|---|
| Numbers events | |||||
| Underweight | 4/353 (1.1%) | 6/353 (1.7%) | 2/353 (0.6%) | 31/353 (8.8%) | 6/353 (1.7%) |
| Normal weight | 78/9,859 (0.8%) | 46/9,859 (0.5%) | 31/9,859 (0.3%) | 229/9,859 (2.3%) | 104/9,859 (1.1%) |
| Overweight | 77/13,787 (0.6%) | 29/13,787 (0.2%) | 18/13,787 (0.1%) | 183/13,787 (1.3%) | 83/13,787 (0.6%) |
| Obese 1 | 59/7,450 (0.8%) | 21/7,450 (0.3%) | 17/7,450 (0.2%) | 95/7,450 (1.3%) | 49/7,450 (0.7%) |
| Obese 2 | 14/3,295 (0.4%) | 9/3,295 (0.3%) | 6/3,295 (0.2%) | 44/3,295 (1.3%) | 23/3,295 (0.7%) |
| Hazard ratio | Hazard ratio | Hazard ratio | Hazard ratio | Hazard ratio | |
| Model 1 (ref = overweight) | |||||
| Underweight | 2.0 (0.7–5.4) | 7.7 (3.1–19) | 4.1 (0.9–18) | 5.7 (3.8–8.4) | 2.5 (1.09–5.9) |
| Normal weight | 1.3 (0.94–1.8) | 2.0 (1.2–3.1) | 2.07 (1.1–3.8) | 1.6 (1.3–1.9) | 1.5 (1.1–2.06) |
| Obese 1 | 1.7 (1.2–2.4) | 1.6 (0.93–2.9) | 2.1 (1.08–4.1) | 1.2 (0.9–1.5) | 1.4 (0.97–2.0) |
| Obese 2 | 1.2 (0.67–2.1) | 2.3 (1.08–5.0) | 2.4 (0.94–6.2) | 1.7 (1.2–2.4) | 2.2 (1.4–3.5) |
| Model 2 (ref = overweight) | |||||
| Underweight | 1.6 (0.58–4.4) | 7.05 (2.8–18) | 3.7 (0.83–17) | 5.2 (3.5–7.7) | 2.3 (0.99–5.3) |
| Normal weight | 1.3 (0.93–1.8) | 1.9 (1.2–3.1) | 2.02 (1.1–3.7) | 1.6 (1.3–1.9) | 1.6 (1.2–2.1) |
| Obese 1 | 1.6 (1.1–2.3) | 1.6 (0.9–2.8) | 2.0 (1.01–3.9) | 1.2 (0.89–1.5) | 1.3 (0.9–1.9) |
| Obese 2 | 1.1 (0.62–2.0) | 2.07 (0.96–4.4) | 2.1 (0.82–5.4) | 1.5 (1.09–2.1) | 1.9 (1.2–3.03) |
| Model 3 (ref = overweight) | |||||
| Underweight | 1.6 (0.58–4.5) | 7.2 (2.9–18) | 3.8 (0.84–17) | 5.3 (3.6–7.9) | 2.4 (1.02–5.5) |
| Normal weight | 1.3 (0.95–1.8) | 2.0 (1.2–3.2) | 2.05 (1.1–3.7) | 1.6 (1.3–2.0) | 1.6 (1.2–2.2) |
| Obese 1 | 1.6 (1.1–2.2) | 1.5 (0.87–2.7) | 2.0 (1.0–3.8) | 1.1 (0.87–1.4) | 1.3 (0.92–1.9) |
| Obese 2 | 1.04 (0.58–1.9) | 1.9 (0.9–4.2) | 2.05 (0.8–5.3) | 1.4 (1.01–2.0) | 1.8 (1.1–2.9) |
| Model 4 (ref = overweight) | |||||
| Underweight | 1.2 (0.44–3.3) | 7.0 (2.8–15) | 3.8 (0.84–17) | 5.2 (3.5–7.8) | 2.4 (1.03–5.6) |
| Normal weight | 0.77 (0.56–1.07) | 2.0 (1.2–3.2) | 2.05 (1.1–3.7) | 1.6 (1.3–2.0) | 1.6 (1.2–2.2) |
| Obese 1 | 1.2 (0.84–1.7) | 1.5 (0.87–2.7) | 2.0 (1.0–3.8) | 1.1 (0.87–1.4) | 1.3 (0.92–1.9) |
| Obese 2 | 0.8 (0.44–1.5) | 1.9 (0.9–4.2) | 2.06 (0.8–5.3) | 1.4 (1.01–2.0) | 1.8 (1.1–2.9) |
MACE: major adverse cardiovascular events (ischemic stroke, acute myocardial infarction, and cardiovascular death); CV: cardiovascular.
Model 1 was adjusted for age, gender, and hip vs. knee replacement surgery. Model 2 was additionally adjusted for heart failure, previous myocardial infarction, chronic ischemic heart disease, atrial fibrillation, peripheral artery disease, cerebrovascular disease, chronic obstructive pulmonary disease, and renal disease. Model 3 was additionally adjusted for diabetes. Model 4 was additionally adjusted for cemented vs. non-cemented prosthesis.