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. 2014 Jul 22;155(10):3806–3816. doi: 10.1210/en.2014-1041

Table 1.

Body Length, Whole-Body Bone Densitometry, Body Fat, and Serum Hormone and Bone Turnover Markers in Male TH and SWR Mice at 8 and 17 Weeks of Age (Mean ± SD)

8 Weeks of Age
17 Weeks of Age
Pstrain Pstrainage
SWR TH SWR TH
n 8 8 10 10
Body length, mm 92.2 (3.9) 95.6 (1.5)a 97.9 (2.7) 102.2 (1.4)a .0016 NS
WAT, g 0.30 (0.06) 1.39 (0.13)a 0.44 (0.16) 1.76 (0.38)a <.001 NS
Serum leptin, ng/mL 6.22 (4.54) 32.88 (12.33)a 5.91 (2.61) 49.67 (32.91)a <.001 NS
Serum insulin, ng/mLb 1.36 (0.69) 2.95 (1.05)a 1.11 (0.49) 4.55 (5.34)a .0289 NS
P1NP, ng/mL 50.02 (19.14) 18.15 (2.59)a 16.89 (4.35) 15.41 (3.62) .0016 .0034
CTX, ng/mL 61.42 (55.06) 86.40 (56.29) 61.40 (43.35) 71.19 (37.26) NS NS

Abbreviation: WAT, white adipose tissue.

a

Bold text indicates significant difference from SWR (P < 0.05, two way ANOVA and Fisher's PLSD).

b

n = 5–6/group.