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. 2014 Jun 16;155(10):3757–3768. doi: 10.1210/en.2013-2051

Figure 3.

Figure 3.

TASK-1 currents control the β-cell plateau potential. A, Mouse β-cell electrical activity in response to 14mM glucose alone or with 250nM A1899 (black bar above trace). B, Plateau potential from where mouse β-cell APs fire, averaged for membrane voltage recordings immediately before (black bar) and 5 minutes after A1899 treatment (grey bar; ±SEM; *, P < .05). C, Human β-cell electrical activity recorded in the presence of high glucose alone (14mM) or with 250nM A1899 (black bar above trace). D, Plateau potentials from where human β-cell APs fire, averaged for voltage recordings immediately before (black bar) and 5 minutes after A1899 treatment (grey bar; ±SEM;*, P < .01).