Comparison 2. Overall tumour non‐response.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall tumour non‐response: 3 vs 24 hour infusion	3	1423	Risk Ratio (IV, Random, 95% CI)	1.07 [0.98, 1.17]
1.1 Breast cancer	2	1041	Risk Ratio (IV, Random, 95% CI)	1.12 [0.96, 1.30]
1.2 Ovarian cancer	1	382	Risk Ratio (IV, Random, 95% CI)	1.03 [0.94, 1.13]
2 Overall tumour non response: 24 vs 96 hour infusion	1		Risk Ratio (IV, Random, 95% CI)	Subtotals only
3 Overall tumour non‐response: 1 vs 3 day schedule	1		Risk Ratio (IV, Random, 95% CI)	Subtotals only