Skip to main content
. Author manuscript; available in PMC: 2014 Sep 16.
Published in final edited form as: Cochrane Database Syst Rev. 2010 May 12;(5):CD004412. doi: 10.1002/14651858.CD004412.pub2
Methods Allocation: randomised.
Blinding: single.
Duration: 16 weeks.
Setting: Veterans Affairs Hospital, USA.
Participants Diagnosis: schizophrenia (DSM-IV).
N=12.
Age: mean ~ 52 years.
Sex: 8M, 2F.
Interventions
  1. Exercise Group: exercise programme 3x a week. 10 minute warm up stretches in addition to walking on a treadmill; participants increased their walking time from 5 minutes on the first day to 30 minutes. N=6

  2. Standard care: participants continued usual care and were placed on waiting list and then received identical intervention at the conclusion of the study. N=6. Data was taken only from the time participants received standard care

Outcomes Mental state: PANSS positive, negative score.
Leaving study early.
Unable to use -
Mental state: PANSS total score (SDs not reported).
Physical fitness: Six Minute Walk Test (SDs not reported).
Weight: BMI, Percentage body fat (SDs not reported - some data for percentage body fat presented as other data)
Notes
Risk of bias
Bias Authors’ judgement Support for judgement
Adequate sequence generation? Low risk Allocation schedule designed by statistician.
Allocation concealment? Unclear risk No details given.
Blinding?
All outcomes
Low risk Single, researcher blinded to group status, untested.
Incomplete outcome data addressed?
All outcomes
High risk 83.3% of participants in the analysis (10/12). Two participants in the exercise arm did not attend first session. These participants were excluded from the results
Free of selective reporting? High risk Several SDs were not reported for PANSS, BMI, and Percentage Body Fat
Free of other bias? High risk Small sample size.