TABLE 7.

Concentrations of BUP and its metabolites in baboon maternal and neonatal plasma at the time of delivery by cesarean section, 1 hour after a 1-mg/kg i.v. bolus dose of BUP to the pregnant baboon

	Concentration of Drug or Metabolite in:
	Maternal Plasma				Neonatal Plasma
	OH-BUP	BUP	TB	EB	OH-BUP	BUP	TB	EB
ng/ml
Study animal
1	213	74	2.4	0.3	29	56	2.9	0.5
2	156	63	16.1	4.8	53	52	4.4	0.5
3	121	52	8.7	3.6	32	56	4.2	0.9
Mean	164	63	9.1	2.9	38	55	3.8	0.6
S.D.	46	11	6.8	2.3	13	2	0.8	0.3