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Model for obesity, inflammation and vascular endothelial changes. ER, endoplasmic reticulum; NFκβ, nuclear factor kappa beta; IL-6, interleukin-6; CRP, C-receptive protein; PAI-1, plasminogen activator inhibitor-1; TNF-α, tumour necrosis factor-alpha; FFA, free fatty acids; SMC, smooth muscle cells; UPR, unfolded protein response.
