TABLE 2.
Effects of different proteins, peptides, and lysophosphocholine on membrane lifetime and pore line tension
Effector | Line tension (γ, pN) | γcontrol/γ | Lifetime decreasea |
---|---|---|---|
PB1-F2 (10 nM)b | 6.6, 8.7 | 1.8, 1.4 | 103, 102 |
tBcl-xL (15 nM)c | 4 | 2 | 102 |
Bax (0.1-0.15 nM)d | 7.7 | 1.2 | 10 |
gp41 (2 μM)e | 6.6 | 1.5 | 102 |
c-Bid (15 nM)f | 2.9 | 1.3 | 25 |
Lyso-PC (300 nM)g | NDh | ND | 10 |
Alpha-toxin | ND | ND | 2 |
γcontrol/γ averaged for several voltages, either calculated or estimated from figures in the papers cited.
The first value shows the value for neutral membrane, and the second value shows the value for charged membrane.
Data from Basañez et al. (5).
Data from Basañez et al. (3).
Data from Chernomordik et al. (14).
Data from G. Basañez (personal communication).
Lyso-PC, lysophosphocholine. Data from Basañez et al. (4).
ND, no data.