FIG. 4.

DCs from uninfected and HCV-infected chimpanzees exhibit the same cytokine and chemokine production. Immature DCs from the uninfected TBDX104 and chronically HCV-infected CB0507 animals were stimulated with the MCM mimic for 24 h. The supernatants from immature (IDC) or MCM mimic-matured (24 h) DCs (MDC) were collected and stored at −20°C before being analyzed by ELISAs. Samples were thawed and tested. RANTES, TNF-α, and CCL7 were assayed by using R&D kits. Data for two sets of supernatants from uninfected and chronically HCV-infected chimpanzee DCs are shown.