Figure 1. Liposomal quercetin (QU) inhibited acute hepatitis induced by Con A. Murine hepatitis was induced by iv injection of Con A. Liposomal QU, free liposomes (lipo), or saline were administered iv 30 min after Con A administration. Mice were sacrificed 4 or 24 h after Con A injection, and blood and liver tissue samples were collected. A, Levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) 4 and 24 h after Con A injection. Data are reported as means±SD for 6 mice per group. *P<0.01, compared to the Con A control (one-way ANOVA followed by the LSD test). B, Photomicrographs of representative H&E-stained liver sections. Black arrows indicate infiltration of inflammatory cells, and white arrows indicate necrotic areas.